The prevalence of allergic symptoms has shown a steady increase in the past few years, and currently affects 20% of the population.
The biological investigation of allergic subjects was considerably improved by the introduction of molecular components, as they provide a better understanding of polysensitisations and/or co-sensitizations and they enable the assessment of symptom severity, while avoiding the risks associated with the use of food allergens.
This department is predominantly involved in the screening of serum specific IgE against over 600 different allergenic products, using either urinary assays or microarray techniques (ISAC test). We also perform assays on a variety of mediators, including histamine, tryptase, and ECP, as well as allergen-specific IgG and IgG4.
In addtition, our laboratory has the ability to perform cellular techniques including the immunological release test and BAT (basophil activation test) by flow cytometry, which are particularly interesting for drug hypersensitivity.